Entry Detail


General Information

Database ID:exR0511125
RNA Name:AKR7A2
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):19303965End Site(bp):19312146
External Links:ENSG00000053371



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HSD17B12
chr11
43680680
43856617
+
PRELID1
chr5
177303799
177306949
+
SAMD11
chr1
923928
944581
+
FEM1A
chr19
4791734
4801273
+
AC073508.2
chr17
40627356
40665141
-
MCAM
chr11
119308529
119321521
-
HSPA1B
chr6
31827738
31830254
+
SHB
chr9
37915898
38069227
-
VIM
chr10
17228241
17237593
+
GDPD3
chr16
30104810
30113537
-
ELFN2
chr22
37367960
37427479
-
DDX3Y
chrY
12904108
12920478
+
CD74
chr5
150400041
150412929
-
HNRNPA2B1
chr7
26173057
26201529
-
ATP1A1
chr1
116372668
116410261
+
MIF
chr22
23894383
23895227
+
NPTX1
chr17
80466834
80477843
-
SMARCE1
chr17
40624962
40648654
-
DDB1
chr11
61299451
61342596
-
TRIO
chr5
14143342
14532128
+
RPLP1
chr15
69452814
69456205
+
CHMP2A
chr19
58551566
58555105
-
HMGA1
chr6
34236873
34246231
+
CAD
chr2
27217369
27243943
+
ID1
chr20
31605283
31606515
+
NR1D2
chr3
23945286
23980617
+
RPL10
chrX
154389955
154409168
+
RASSF3
chr12
64507001
64697564
+
MESD
chr15
80946289
80989828
-
RPS8
chr1
44775251
44778779
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP000317.2
chr21
34073592
34360033
+
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.