Entry Detail


General Information

Database ID:exR0511128
RNA Name:AKT1S1
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):49869033End Site(bp):49878459
External Links:ENSG00000204673



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
YIPF3
chr6
43511832
43516985
-
FOXRED2
chr22
36487190
36507101
-
FAM86C1
chr11
71787510
71801237
+
BABAM2
chr2
27889941
28338901
+
PABPN1
chr14
23321289
23326185
+
BBS10
chr12
76344474
76348415
-
ESYT1
chr12
56118250
56144671
+
ZNF585A
chr19
37106734
37172741
-
SEC62
chr3
169966635
169998373
+
EEF1G
chr11
62559596
62574086
-
SEPHS1
chr10
13317428
13348298
-
STAG3
chr7
100177563
100221488
+
CBX1
chr17
48070052
48101478
-
KIAA2013
chr1
11919591
11926428
-
IRF2BP2
chr1
234604269
234609525
-
NOMO3
chr16
16232528
16294811
+
KAT7
chr17
49788681
49835026
+
ZFP36L1
chr14
68787660
68796253
-
PODXL
chr7
131500262
131558217
-
CRABP2
chr1
156699606
156705816
-
PILRB
chr7
100352176
100367733
+
AGO2
chr8
140520156
140635633
-
DPY19L1
chr7
34928876
35038271
-
ATF5
chr19
49928702
49933935
+
ID1
chr20
31605283
31606515
+
MYL6
chr12
56158161
56163496
+
TMEM256-PLSCR3
chr17
7389734
7404097
-
SLC6A6
chr3
14402576
14489349
+
NLRX1
chr11
119166568
119184016
+
HNRNPUL1
chr19
41262496
41307787
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC113189.2
chr17
7420103
7444081
+
AC113189.4
chr17
7439506
7445966
+
AC079949.1
chr12
127142029
127146532
-
AP001626.1
chr21
42648271
42651244
-
HCG18
chr6
30286690
30327382
-
SLX1A-SULT1A3
chr16
30193892
30204310
+
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.