Entry Detail


General Information

Database ID:exR0511129
RNA Name:AKT3
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):243488233End Site(bp):243851079
External Links:ENSG00000117020



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NUP107
chr12
68686951
68745809
+
FUCA1
chr1
23845077
23868294
-
HNRNPK
chr9
83968083
83980616
-
RPL37
chr5
40825262
40835222
-
EDEM2
chr20
35115364
35147336
-
PRDX6
chr1
173477330
173488815
+
HLA-C
chr6
31268749
31272130
-
MAP3K7
chr6
90513573
90587072
-
SRSF4
chr1
29147743
29181900
-
IPMK
chr10
58191517
58267894
-
POLR2F
chr22
37952607
38041915
+
IST1
chr16
71845996
71931199
+
ID1
chr20
31605283
31606515
+
L1TD1
chr1
62194849
62212328
+
SF3B1
chr2
197388515
197435091
-
SDCCAG8
chr1
243256034
243500091
+
POLR1D
chr13
27620742
27744237
+
ESRP1
chr8
94641074
94707466
+
LAPTM4B
chr8
97775057
97853013
+
AKT2
chr19
40230317
40285536
-
STK4
chr20
44966479
45080021
+
HNRNPL
chr19
38836388
38852347
-
PAPOLA
chr14
96501433
96567111
+
PKN1
chr19
14433053
14471867
+
IL6R
chr1
154405193
154469450
+
TIMM10B
chr11
6481501
6484681
+
RPL13A
chr19
49487554
49492308
+
RTN4R
chr22
20241415
20283246
-
ANKFY1
chr17
4163821
4263995
-
SGSH
chr17
80206716
80220923
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
RMRP
chr9
35657751
35658018
-
SNHG1
chr11
62851984
62855953
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.