Entry Detail


General Information

Database ID:exR0511130
RNA Name:AKTIP
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):53491040End Site(bp):53504411
External Links:ENSG00000166971



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AHCYL1
chr1
109984765
110023742
+
AP002990.1
chr11
62559603
62591531
-
ATXN2L
chr16
28823035
28837237
+
EEF1G
chr11
62559596
62574086
-
EI24
chr11
125569280
125584684
+
EIF3H
chr8
116642130
116766925
-
ERG28
chr14
75649791
75660876
-
FGF2
chr4
122826708
122898236
+
FLRT3
chr20
14322985
14337614
-
FRAS1
chr4
78057323
78544269
+
HILPDA
chr7
128455849
128458418
+
HMGN3
chr6
79201245
79234738
-
MT-CO3
chrMT
9207
9990
+
NAPG
chr18
10525905
10552764
+
PIGX
chr3
196639775
196736007
+
PPP4R3B
chr2
55547292
55618880
-
PTGES3
chr12
56663341
56688408
-
SH3KBP1
chrX
19533977
19887600
-
SLC7A5
chr16
87830023
87869507
-
TMCO3
chr13
113491021
113554590
+
TMX1
chr14
51240162
51257655
+
TRIM71
chr3
32817997
32897824
+
TSPAN6
chrX
100627108
100639991
-
TUFM
chr16
28842411
28846348
-
UQCR10
chr22
29767369
29770413
+
VCPIP1
chr8
66628487
66667231
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.