Entry Detail


General Information

Database ID:exR0511131
RNA Name:ALAD
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):113386312End Site(bp):113401290
External Links:ENSG00000148218



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SUSD2
chr22
24181487
24189106
+
EIF4G2
chr11
10797050
10808940
-
RTL6
chr22
44492583
44498233
-
FAM32A
chr19
16185380
16192046
+
PKM
chr15
72199029
72231822
-
MRPL12
chr17
81703367
81707517
+
NEK1
chr4
169392857
169612629
-
NAPB
chr20
23374519
23421519
-
TAF6L
chr11
62771357
62787342
+
GAPDH
chr12
6534512
6538374
+
UBR5
chr8
102252273
102412759
-
CHD4
chr12
6570082
6614524
-
TIPIN
chr15
66336191
66386746
-
ZCCHC8
chr12
122471599
122501073
-
HNRNPK
chr9
83968083
83980616
-
AC139530.2
chr17
81703371
81720539
+
ARHGDIA
chr17
81867721
81871378
-
RPL4
chr15
66498015
66524532
-
PFN1
chr17
4945652
4949061
-
HLA-DRA
chr6
32439878
32445046
+
POU5F1
chr6
31164337
31180731
-
YBX3
chr12
10699089
10723323
-
RAB13
chr1
153981617
153986358
-
RPL41
chr12
56116590
56117967
+
HSPBP1
chr19
55262223
55280381
-
PLEC
chr8
143915147
143976734
-
HELLS
chr10
94501434
94613905
+
PRC1
chr15
90966040
90995629
-
CRMP1
chr4
5748084
5893086
-
C17orf100
chr17
6651762
6693202
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC068831.7
chr15
91022766
91023200
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.