Entry Detail


General Information

Database ID:exR0511135
RNA Name:ALCAM
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):105366909End Site(bp):105576900
External Links:ENSG00000170017



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZNF525
chr19
53365693
53392217
+
RPL34
chr4
108620566
108630412
+
EIF5A
chr17
7306999
7312463
+
OAZ1
chr19
2269509
2273490
+
MT-CO1
chrMT
5904
7445
+
SLC10A7
chr4
146253975
146521964
-
FBXO45
chr3
196568611
196589059
+
ZNF664
chr12
123971845
124015439
+
EIF3F
chr11
7970251
8001862
+
NUDT5
chr10
12165330
12196144
-
NOP56
chr20
2652593
2658393
+
CMTM6
chr3
32481312
32502852
-
POLR2E
chr19
1086574
1095380
-
FRAS1
chr4
78057323
78544269
+
VAMP3
chr1
7771296
7781432
+
ATP5MG
chr11
118401606
118431496
+
FKBP8
chr19
18531751
18544077
-
TMEM107
chr17
8172457
8176399
-
ADK
chr10
74151202
74709963
+
CYTIP
chr2
157414619
157488961
-
CDH3
chr16
68636189
68722616
+
KBTBD2
chr7
32868172
32894131
-
EIF3E
chr8
108201216
108435333
-
RPLP0
chr12
120196699
120201235
-
PRRC2B
chr9
131373636
131500197
+
RBM5
chr3
50088919
50119021
+
PPME1
chr11
74171267
74254703
+
BTG1
chr12
92140278
92145846
-
IGFBP2
chr2
216632828
216664436
+
SPRED1
chr15
38252836
38357249
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC024940.6
chr12
31280422
31280895
-
AD000090.1
chr19
35557956
35581954
+
LINC00992
chr5
117415509
117546298
+
MALAT1
chr11
65497688
65506516
+
PRNCR1
chr8
127079874
127092600
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.