Entry Detail


General Information

Database ID:exR0511136
RNA Name:ALDH16A1
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):49453225End Site(bp):49471050
External Links:ENSG00000161618



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MED22
chr9
133338312
133348131
-
SOX4
chr6
21593751
21598619
+
SLC52A2
chr8
144354135
144361272
+
LARGE2
chr11
45921621
45929096
+
EEF1A1
chr6
73515750
73523797
-
FASTK
chr7
151076593
151080866
-
FAT1
chr4
186587794
186726722
-
LGALS9
chr17
27629798
27649560
+
PPP1R10
chr6
30600413
30618612
-
GRB10
chr7
50590063
50793462
-
ATP6V1G2-DDX39B
chr6
31530219
31546608
-
SLC25A11
chr17
4937130
4940053
-
GSPT1
chr16
11868128
11916082
-
HOXB3
chr17
48548870
48604912
-
THOP1
chr19
2785503
2815807
+
CYB5B
chr16
69424619
69466264
+
ARFGAP1
chr20
63272785
63289790
+
CBX6
chr22
38861422
38872249
-
CTNNA1
chr5
138610967
138935034
+
B3GALT6
chr1
1232237
1235041
+
ADAMTS1
chr21
26835755
26845409
-
DHX36
chr3
154272546
154324487
-
ISG20L2
chr1
156721891
156728799
-
CDC34
chr19
531760
542092
+
ZNRF2
chr7
30284597
30367689
+
BCR
chr22
23179704
23318037
+
EEF2
chr19
3976056
3985463
-
RBM15
chr1
110338506
110346681
+
GPATCH2L
chr14
76151916
76254342
+
DDX39B
chr6
31530219
31542448
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020928.2
chr19
36773712
36775908
-
AC067852.1
chr17
42536510
42562062
+
AC132217.1
chr11
2129121
2129964
-
VPS9D1-AS1
chr16
89711856
89718165
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.