Entry Detail


General Information

Database ID:exR0511141
RNA Name:ALDH1B1
RNA Type:mRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):38392702End Site(bp):38398661
External Links:ENSG00000137124



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
UPF1
chr19
18831938
18868236
+
ISG20L2
chr1
156721891
156728799
-
STAU1
chr20
49113339
49188367
-
SNURF
chr15
24954986
24977850
+
P4HB
chr17
81843161
81860624
-
GLYR1
chr16
4803203
4847288
-
POLRMT
chr19
617221
633537
-
C9orf129
chr9
93318199
93346414
-
LSP1
chr11
1852970
1892267
+
HNRNPU
chr1
244840638
244864560
-
TPCN1
chr12
113221050
113298585
+
LRG1
chr19
4536402
4540036
-
RNF150
chr4
140859807
141212877
-
CLDN6
chr16
3014712
3020071
-
TXNDC5
chr6
7881517
7910788
-
SSBP1
chr7
141738334
141787922
+
PPP1R12A
chr12
79773563
79935460
-
YIPF1
chr1
53851719
53889798
-
BLOC1S5-TXNDC5
chr6
7881522
8064364
-
WDR70
chr5
37379285
37753435
+
SPOP
chr17
49598884
49678163
-
TP53
chr17
7661779
7687550
-
SNRPN
chr15
24823637
24978723
+
NOLC1
chr10
102152176
102163871
+
TMEM132B
chr12
125186836
125662377
+
HMGA1
chr6
34236873
34246231
+
LY75
chr2
159803355
159904756
-
PTP4A1
chr6
63521746
63583436
+
HSP90AB1
chr6
44246166
44253888
+
KLC2
chr11
66257294
66267860
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020663.1
chr16
4730115
4752565
-
AP003175.1
chr11
75069243
75096964
-
SNHG3
chr1
28505980
28510892
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.