Entry Detail


General Information

Database ID:exR0511144
RNA Name:ALDH2
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):111766887End Site(bp):111817532
External Links:ENSG00000111275



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
WASF3
chr13
26557683
26688948
+
RACK1
chr5
181236897
181248096
-
ANKS1A
chr6
34889255
35091406
+
NME2
chr17
51165435
51171747
+
EIF5A
chr17
7306999
7312463
+
ZNF891
chr12
133106817
133130473
-
NPM1
chr5
171387116
171411137
+
LYSMD1
chr1
151159748
151165948
-
PEX5
chr12
7188685
7218574
+
RBM39
chr20
35701347
35742312
-
LAMA5
chr20
62307955
62367312
-
PITPNM1
chr11
67491768
67506263
-
RPL28
chr19
55385345
55403250
+
ANKRD11
chr16
89267630
89490561
-
TUBA1C
chr12
49188736
49274603
+
RBPJ
chr4
26163455
26435131
+
PRPF19
chr11
60890547
60906585
-
PRTG
chr15
55611544
55743152
-
ZNF671
chr19
57719751
57727624
-
CSK
chr15
74782057
74803198
+
AC002996.1
chr12
111753890
111791418
+
GPT2
chr16
46884362
46931289
+
PTPN9
chr15
75463251
75579315
-
SIRT7
chr17
81911939
81921323
-
DR1
chr1
93345907
93369493
+
ACTB
chr7
5527148
5563784
-
AC010422.3
chr19
12643831
12648397
-
RPL13
chr16
89560657
89566828
+
APOBEC3G
chr22
39077067
39087743
+
SIKE1
chr1
114769479
114780685
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC092117.1
chr16
2777319
2780568
+
AC108134.2
chr16
3156736
3157483
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.