Entry Detail


General Information

Database ID:exR0511146
RNA Name:ALDH3A2
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):19648136End Site(bp):19685760
External Links:ENSG00000072210



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BLM
chr15
90717346
90816166
+
C4orf3
chr4
119296419
119304445
-
KMT2D
chr12
49018975
49059774
-
EIF5A
chr17
7306999
7312463
+
PRSS16
chr6
27247701
27256624
+
NPM1
chr5
171387116
171411137
+
ERGIC3
chr20
35542021
35557634
+
BST2
chr19
17402939
17405630
-
IQGAP1
chr15
90388242
90502239
+
HMGCR
chr5
75336329
75362101
+
MTRNR2L3
chr20
57358447
57359498
-
PEA15
chr1
160205337
160215376
+
BOD1
chr5
173607145
173616659
-
TUBA1A
chr12
49184795
49189080
-
SPCS1
chr3
52704955
52711148
+
DGLUCY
chr14
91060333
91225632
+
GID8
chr20
62938147
62948475
+
ENSA
chr1
150600851
150629612
-
RSL24D1
chr15
55180806
55197049
-
ARPC2
chr2
218217141
218254356
+
ZNF431
chr19
21142024
21196053
+
MFGE8
chr15
88898683
88913381
-
MIF
chr22
23894383
23895227
+
MPC2
chr1
167916675
167937072
-
TNFRSF14
chr1
2555639
2565382
+
SOX8
chr16
981770
986979
+
PDZD8
chr10
117277274
117375440
-
BCR
chr22
23179704
23318037
+
AK2
chr1
33007940
33080996
-
AMACR
chr5
33986165
34008104
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19b-3p
chr13
91351245
91351267
+
hsa-miR-27a-3p
chr19
13836447
13836467
-
hsa-miR-27b-3p
chr9
95085505
95085525
+
hsa-miR-301a-3p
chr17
59151149
59151171
-
hsa-miR-431-5p
chr14
100881026
100881046
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
SCARNA9
chr11
93721513
93721865
+
SNHG16
chr17
76557764
76565348
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.