Entry Detail


General Information

Database ID:exR0511151
RNA Name:ALDH6A1
RNA Type:mRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):74056847End Site(bp):74084492
External Links:ENSG00000119711



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SYNCRIP
chr6
85607785
85643792
-
SRPRB
chr3
133784023
133825772
+
HNRNPA1L2
chr13
52642425
52643796
+
SLC12A2
chr5
128083766
128189677
+
KIAA0556
chr16
27550133
27780369
+
RPL8
chr8
144789765
144792587
-
ATP5PB
chr1
111448864
111462773
+
CFL1
chr11
65823022
65862026
-
NOP53
chr19
47745546
47757058
+
SFRP2
chr4
153780591
153789083
-
METAP1
chr4
98995659
99062809
+
PPP1R37
chr19
45091396
45148077
+
DNAJA2
chr16
46955362
46973674
-
ZNF544
chr19
58228594
58277495
+
COLGALT1
chr19
17555649
17583162
+
SRSF1
chr17
58000919
58007346
-
BRD2
chr6
32968594
32981505
+
EIF1
chr17
41688885
41692668
+
BOD1
chr5
173607145
173616659
-
BCL2L13
chr22
17628855
17730855
+
COPS4
chr4
83034447
83075818
+
TSPAN3
chr15
77041404
77083984
-
CCND1
chr11
69641156
69654474
+
LIN28A
chr1
26410817
26429728
+
PTPRU
chr1
29236516
29326813
+
CALM3
chr19
46601074
46610782
+
AC015813.2
chr17
57989038
58007246
-
RACK1
chr5
181236897
181248096
-
PRPSAP2
chr17
18840085
18931287
+
HSP90AB1
chr6
44246166
44253888
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
PSMA3-AS1
chr14
58265365
58298134
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.