Entry Detail


General Information

Database ID:exR0511152
RNA Name:ALDH7A1
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):126531200End Site(bp):126595362
External Links:ENSG00000164904



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CNDP2
chr18
74495816
74523454
+
SLC2A3
chr12
7919230
7936187
-
CRISPLD1
chr8
74984505
75034558
+
NUCKS1
chr1
205712822
205750182
-
LIN28B
chr6
104936616
105083332
+
HERC2
chr15
28111040
28322172
-
CALCOCO1
chr12
53708517
53727745
-
DUSP16
chr12
12473282
12562863
-
NASP
chr1
45583846
45618904
+
WDR24
chr16
684622
690444
-
SBNO1
chr12
123289109
123364847
-
CIB2
chr15
78104606
78131535
-
EEF2
chr19
3976056
3985463
-
SF3B1
chr2
197388515
197435091
-
CAPZA1
chr1
112619805
112671616
+
KHDRBS1
chr1
32013868
32060850
+
TUBA1C
chr12
49188736
49274603
+
SOX13
chr1
204073115
204127743
+
EIF3C
chr16
28688558
28735730
+
ERLIN2
chr8
37736601
37758422
+
CD276
chr15
73683966
73714514
+
DDHD2
chr8
38225218
38275558
+
CYTL1
chr4
5014586
5019458
-
WDHD1
chr14
54938949
55027105
-
EIF4H
chr7
74174245
74197101
+
KANSL3
chr2
96593170
96642787
-
SCRN1
chr7
29920104
29990289
-
DPPA4
chr3
109326141
109337572
-
ZNF589
chr3
48241100
48299253
+
RPL23
chr17
38847860
38853764
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012467.2
chr3
53858994
53861576
-
AC016876.2
chr17
7581964
7584086
-
SNHG14
chr15
24978583
25420336
+
SOX21-AS1
chr13
94703454
94803430
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.