Entry Detail


General Information

Database ID:exR0511154
RNA Name:ALDH9A1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):165662216End Site(bp):165698863
External Links:ENSG00000143149



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
FYN
chr6
111660332
111873452
-
NIPSNAP1
chr22
29554808
29581327
-
GSE1
chr16
85169525
85676204
+
KCNMB4
chr12
70366290
70434292
+
RPS15
chr19
1438358
1440494
+
HES1
chr3
194136148
194138732
+
B4GALT6
chr18
31622247
31685836
-
FBRSL1
chr12
132489551
132585188
+
TCF19
chr6
31158547
31167159
+
RABEP2
chr16
28904421
28936526
-
MORF4L2
chrX
103675496
103688158
-
PCK2
chr14
24094053
24110598
+
LRRFIP1
chr2
237627587
237813682
+
SRSF2
chr17
76734115
76737374
-
ITCH
chr20
34363241
34540748
+
ZNF384
chr12
6666477
6689572
-
SPARC
chr5
151661096
151686975
-
CD55
chr1
207321376
207386804
+
ENO1
chr1
8861000
8879190
-
RPS6
chr9
19375715
19380236
-
DDOST
chr1
20651767
20661544
-
SRSF3
chr6
36594353
36605600
+
KHSRP
chr19
6413348
6424794
-
RALY
chr20
33993646
34108308
+
SLC4A8
chr12
51391317
51515763
+
MRRF
chr9
122264603
122331337
+
MCM7
chr7
100092728
100101940
-
DVL3
chr3
184155377
184173614
+
GJA1
chr6
121435595
121449727
+
MTA1
chr14
105419820
105470729
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-1270
chr19
20399320
20399342
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC026740.1
chr5
675826
676616
+
AL139819.1
chr10
100335563
100346390
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.