Entry Detail


General Information

Database ID:exR0511155
RNA Name:ALDOA
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):30064164End Site(bp):30070457
External Links:ENSG00000149925



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC104452.1
chr3
49416777
49429314
-
AL590764.2
chrX
71103987
71111575
-
AKAP8L
chr19
15380050
15419141
-
AC007192.1
chr19
18153158
18178117
+
ADSL
chr22
40346500
40390463
+
AC092143.1
chr16
89919165
89936092
+
ACLY
chr17
41866917
41930542
-
ACTN4
chr19
38647649
38731589
+
AKAP8
chr19
15353385
15379798
-
AKIRIN1
chr1
38991276
39006059
+
ACTA1
chr1
229431245
229434098
-
AL365205.1
chr6
41780349
41790141
+
AFG3L2
chr18
12328944
12377227
-
AL136454.1
chr1
192716132
192716653
+
AHDC1
chr1
27534035
27604431
-
AHCYL1
chr1
109984765
110023742
+
ADCY1
chr7
45574140
45723116
+
AHRR
chr5
271670
438291
+
AL117348.2
chr1
225886696
225924278
-
AL109827.1
chr20
35632340
35674544
-
AC010132.3
chr7
42909273
42932174
-
ACTG1
chr17
81509971
81523847
-
AC008763.3
chr19
7678501
7682854
+
AHSA1
chr14
77457870
77469472
+
AC040162.1
chr16
67929614
67936017
-
AC011448.1
chr19
19516227
19536076
+
ACP1
chr2
264140
278283
+
AC131160.1
chr3
183815568
183884889
-
AC245033.1
chr15
82536788
82573194
-
AC010422.3
chr19
12643831
12648397
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-122-5p
chr18
58451088
58451109
+
hsa-miR-146a-5p
chr5
160485372
160485393
+
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-574-5p
chr4
38868056
38868078
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC016747.4
chr2
61115787
61164825
+
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC079781.5
chr7
97851688
97972985
-
AC091564.7
chr11
6610883
6616594
-
AC114271.1
chr19
10333436
10336248
+
AC244090.1
chrX
154424380
154428479
-
AD000090.1
chr19
35557956
35581954
+
AL117378.1
chr6
131901963
131920565
+
AC005632.3
chr16
21626742
21627569
+
AC239799.1
chr1
146235806
146237807
+
AL031005.1
chr1
21266082
21267251
+
AL355075.4
chr14
20343048
20343685
-
AL391422.3
chr6
3831933
3855737
+
AP005263.1
chr18
9102736
9254346
+
DANCR
chr4
52712404
52720351
+
MIR3142HG
chr5
160438594
160487426
+
MIR762HG
chr16
30875222
30895220
+
SNHG5
chr6
85650491
85678932
-
SNHG8
chr4
118278709
118285316
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.