Entry Detail


General Information

Database ID:exR0511157
RNA Name:ALDOC
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):28573115End Site(bp):28576948
External Links:ENSG00000109107



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC005943.1
chr19
1578339
1605445
-
AC024592.3
chr19
5866171
5903787
-
AC091167.2
chr15
90249556
90272208
+
AC138811.2
chr16
18788063
18801519
-
ACSL3
chr2
222860942
222944639
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AFG3L2
chr18
12328944
12377227
-
AHCY
chr20
34280268
34311802
-
AK3
chr9
4709556
4742043
-
AL136454.1
chr1
192716132
192716653
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC025031.2
chr12
46371463
46373778
+
AC060780.1
chr17
43148368
43171037
-
AC104109.4
chr5
134205614
134371044
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.