Entry Detail


General Information

Database ID:exR0511239
RNA Name:ANAPC5
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):121308245End Site(bp):121399896
External Links:ENSG00000089053



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCG1
chr21
42199689
42297244
+
ABL1
chr9
130713016
130887675
+
AC010323.1
chr19
8308283
8321379
-
AC068946.1
chr2
219075329
219170827
-
AC073508.2
chr17
40627356
40665141
-
ACTG1
chr17
81509971
81523847
-
ADIPOR2
chr12
1688574
1788674
+
AGK
chr7
141551278
141655244
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020663.1
chr16
4730115
4752565
-
AC091564.7
chr11
6610883
6616594
-
AC104971.3
chr18
58659858
58660524
+
AC129492.1
chr17
8079482
8081565
+
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.