Entry Detail


General Information

Database ID:exR0511308
RNA Name:ANKRD52
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):56237807End Site(bp):56258384
External Links:ENSG00000139645



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC10
chr6
43427366
43450427
+
ACTG1
chr17
81509971
81523847
-
AHCY
chr20
34280268
34311802
-
AL513165.2
chr9
37512547
37592469
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-31-5p
chr9
21512158
21512178
-
hsa-miR-124-3p
chr8
64379210
64379231
+
hsa-miR-130b-3p
chr22
21653354
21653375
+
hsa-miR-448
chrX
114823524
114823545
+
hsa-miR-525-3p
chr19
53697584
53697605
+
hsa-miR-524-3p
chr19
53711054
53711074
+
hsa-miR-449b-5p
chr5
55170706
55170727
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-708-5p
chr11
79402077
79402099
-
hsa-miR-1224-5p
chr3
184241405
184241423
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009022.1
chr16
69976297
70065948
-
AC073365.1
chr3
191425493
191591097
+
AGAP11
chr10
86970741
87010126
+
AL136982.1
chr10
86992406
87010203
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.