Entry Detail


General Information

Database ID:exR0511364
RNA Name:AP2M1
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):184174689End Site(bp):184184091
External Links:ENSG00000161203



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AC011448.1
chr19
19516227
19536076
+
AC087289.3
chr17
75898645
75930129
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ACVR2B
chr3
38453890
38493142
+
ADGRG1
chr16
57610652
57665580
+
AGBL2
chr11
47659591
47715389
-
AGBL5
chr2
27042364
27070622
+
AGPS
chr2
177392757
177559299
+
AIP
chr11
67483026
67491103
+
AK4
chr1
65147549
65232145
+
AKIRIN2
chr6
87674860
87702233
-
AKT1
chr14
104769349
104795751
-
AL133352.1
chr10
100505628
100529881
-
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3652
chr12
103930425
103930442
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC006141.1
chr17
51249579
51251748
-
AC079781.5
chr7
97851688
97972985
-
AC092490.1
chr12
8788253
8795789
+
AC099329.1
chr3
42785087
42852428
-
AGAP1-IT1
chr2
235505751
235507566
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.