Entry Detail


General Information

Database ID:exR0511388
RNA Name:APEX1
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):20455191End Site(bp):20457772
External Links:ENSG00000100823



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASS
chr7
122073549
122144255
-
ABHD17B
chr9
71862452
71910931
-
ABTB1
chr3
127672935
127680926
+
AC010422.3
chr19
12643831
12648397
-
AC068946.1
chr2
219075329
219170827
-
AC073508.2
chr17
40627356
40665141
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADAM15
chr1
155050566
155062775
+
ADAMTS6
chr5
65148738
65481920
-
ADGRL1
chr19
14147743
14206187
-
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AL109827.1
chr20
35632340
35674544
-
ALDH16A1
chr19
49453225
49471050
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.2
chr17
19092974
19096837
+
AC132217.1
chr11
2129121
2129964
-
AL021707.1
chr22
38739003
38749041
+
AL096870.2
chr14
24209646
24215987
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.