Entry Detail


General Information

Database ID:exR0511455
RNA Name:ARF1
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):228082660End Site(bp):228099212
External Links:ENSG00000143761



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006064.6
chr12
6556886
6607367
-
AC011455.2
chr19
38915404
38949855
-
AC073610.2
chr12
48903503
48957365
-
ACADVL
chr17
7217125
7225266
+
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ACTR10
chr14
58200080
58235636
+
ACTR2
chr2
65227753
65271253
+
ADGRA2
chr8
37784191
37844896
+
AFDN
chr6
167826922
167972023
+
AGO4
chr1
35808016
35857890
+
AGPAT2
chr9
136673143
136687457
-
AGPAT3
chr21
43865223
43987592
+
AIMP2
chr7
6009255
6023834
+
AKAP8L
chr19
15380050
15419141
-
AKAP9
chr7
91940867
92110673
+
AL713999.1
chr1
155169409
155187272
-
ALDH5A1
chr6
24494867
24537207
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3610
chr8
116874740
116874759
-
hsa-miR-3620-3p
chr1
228097320
228097341
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC026362.1
chr12
122975320
122982907
+
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.