Entry Detail


General Information

Database ID:exR0511495
RNA Name:ARHGDIA
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):81867721End Site(bp):81871378
External Links:ENSG00000141522



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABI2
chr2
203328239
203447728
+
AC010132.3
chr7
42909273
42932174
-
AC011005.1
chr7
129126518
129130793
+
AC018512.1
chr15
43772617
43799133
-
AC020909.1
chr19
50415799
50428409
+
AC093525.2
chr16
2496032
2520218
+
AC120057.2
chr17
7240427
7244635
-
ACBD6
chr1
180269653
180502954
-
ACER3
chr11
76860867
77026797
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADAR
chr1
154582057
154628013
-
ADORA2A
chr22
24417879
24442357
+
AGRN
chr1
1020120
1056118
+
AKT1
chr14
104769349
104795751
-
AKT1S1
chr19
49869033
49878459
-
ALAD
chr9
113386312
113401290
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-16-5p
chr3
160404754
160404775
+
hsa-miR-339-5p
chr7
1022990
1023012
-
hsa-miR-497-5p
chr17
7017979
7017999
-
hsa-miR-588
chr6
126484646
126484666
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-744-5p
chr17
12081909
12081930
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC060780.1
chr17
43148368
43171037
-
AC099329.1
chr3
42785087
42852428
-
AC109460.3
chr16
28974804
28990775
+
AC124068.2
chr15
89335053
89336161
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.