Entry Detail


General Information

Database ID:exR0511517
RNA Name:ARID3B
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):74541177End Site(bp):74598131
External Links:ENSG00000179361



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006538.2
chr19
2717769
2740048
-
AC135050.2
chr16
31083439
31094956
-
ADAM10
chr15
58588809
58749791
-
ADAM9
chr8
38996869
39105261
+
AICDA
chr12
8602170
8612867
-
AKIRIN1
chr1
38991276
39006059
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7b-5p
chr22
46113691
46113712
+
hsa-let-7d-5p
chr9
94178841
94178862
+
hsa-miR-22-3p
chr17
1713914
1713935
-
hsa-miR-147a
chr9
120244985
120245004
-
hsa-miR-205-5p
chr1
209432166
209432187
+
hsa-let-7g-5p
chr3
52268336
52268357
-
hsa-let-7i-5p
chr12
62603691
62603712
+
hsa-miR-760
chr1
93846880
93846899
+
hsa-miR-1286
chr22
20249145
20249165
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC024940.6
chr12
31280422
31280895
-
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.