Entry Detail


General Information

Database ID:exR0511577
RNA Name:ARPP19
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):52547045End Site(bp):52569883
External Links:ENSG00000128989



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD1
chrX
153724856
153744755
+
ABL2
chr1
179099330
179229684
-
AC010422.3
chr19
12643831
12648397
-
ACAT2
chr6
159762045
159779112
+
ACTG1
chr17
81509971
81523847
-
AHCYL2
chr7
129225023
129430211
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-24-3p
chr9
95086064
95086085
+
hsa-miR-105-5p
chrX
152394458
152394480
-
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-135a-5p
chr12
97563834
97563856
+
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-323a-3p
chr14
101025782
101025802
+
hsa-miR-135b-5p
chr1
205448361
205448383
-
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC078881.1
chr4
177442519
177681381
+
AC132217.1
chr11
2129121
2129964
-
AL137230.2
chr14
89628921
89642671
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.