Entry Detail


General Information

Database ID:exR0511676
RNA Name:ATF7IP
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):14365632End Site(bp):14502935
External Links:ENSG00000171681



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD5
chr3
43690108
43734371
+
AC026954.2
chr17
7312661
7319174
-
ACADVL
chr17
7217125
7225266
+
ACSF3
chr16
89088375
89164121
+
ACTB
chr7
5527148
5563784
-
ACTR3
chr2
113890063
113962596
+
AL133352.1
chr10
100505628
100529881
-
AL136454.1
chr1
192716132
192716653
+
AL360181.3
chr10
133380017
133420271
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19a-3p
chr13
91350939
91350961
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC019069.1
chr2
74832655
74833987
-
AC090587.2
chr11
3854612
3855399
+
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.