Entry Detail


General Information

Database ID:exR0511715
RNA Name:ATP1A1
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):116372668End Site(bp):116410261
External Links:ENSG00000163399



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004922.1
chr7
99325879
99394653
+
AC005943.1
chr19
1578339
1605445
-
AC007192.1
chr19
18153158
18178117
+
AC008982.1
chr19
38817471
38840178
-
AC012254.2
chr18
47108188
47176345
-
AC027644.4
chr7
66628958
66811189
+
AC105052.1
chr7
102582523
102642869
-
AC110275.1
chr8
43018424
43077334
+
AC120057.2
chr17
7240427
7244635
-
AC139530.2
chr17
81703371
81720539
+
ACKR3
chr2
236567787
236582354
+
ACTC1
chr15
34790230
34795549
-
ACTG1
chr17
81509971
81523847
-
ADCY3
chr2
24819169
24919839
-
AHDC1
chr1
27534035
27604431
-
AK3
chr9
4709556
4742043
-
AK9
chr6
109492856
109691217
-
AKR7A2
chr1
19303965
19312146
-
AL136454.1
chr1
192716132
192716653
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-5100
chr10
42997630
42997651
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC051619.6
chr15
45198517
45199139
-
AC067930.1
chr8
143579636
143580670
+
AC129492.1
chr17
8079482
8081565
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL118558.3
chr14
101948347
101949425
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.