Entry Detail


General Information

Database ID:exR0511747
RNA Name:ATP6V1B2
RNA Type:mRNA
Chromosome:chr8
Starnd:+
Coordinate:
Start Site(bp):20197381End Site(bp):20226819
External Links:ENSG00000147416



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGBL5
chr2
27042364
27070622
+
AL136295.1
chr14
24189157
24213473
-
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19a-3p
chr13
91350939
91350961
+
hsa-miR-19b-3p
chr13
91351245
91351267
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-302a-3p
chr4
112648186
112648208
-
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302c-3p
chr4
112648366
112648388
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-520d-3p
chr19
53720149
53720170
+
hsa-miR-1270
chr19
20399320
20399342
-
hsa-miR-302e
chr11
7234771
7234787
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.