Entry Detail


General Information

Database ID:exR0511779
RNA Name:ATXN2L
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):28823035End Site(bp):28837237
External Links:ENSG00000168488



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005726.1
chr17
28455752
28614185
-
AC011511.4
chr19
10315471
10320678
-
ADA
chr20
44619522
44652233
-
ADAMTS10
chr19
8580240
8610735
-
AKTIP
chr16
53491040
53504411
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-184
chr15
79209840
79209861
+
hsa-miR-424-5p
chrX
134546680
134546701
-
hsa-miR-449a
chr5
55170586
55170607
-
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-449b-5p
chr5
55170706
55170727
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-708-5p
chr11
79402077
79402099
-
hsa-miR-1286
chr22
20249145
20249165
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC027307.3
chr19
1440839
1441938
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.