Entry Detail


General Information

Database ID:exR0511808
RNA Name:B2M
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):44711487End Site(bp):44718877
External Links:ENSG00000166710



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC138811.2
chr16
18788063
18801519
-
ADAR
chr1
154582057
154628013
-
AGPAT5
chr8
6708642
6761503
+
AC011511.1
chr19
10305427
10316009
-
AIFM1
chrX
130129362
130165887
-
AK4
chr1
65147549
65232145
+
ACLY
chr17
41866917
41930542
-
ABT1
chr6
26596953
26600739
+
AK2
chr1
33007940
33080996
-
ACADSB
chr10
123008979
123058290
+
ACP5
chr19
11574660
11579008
-
ACP1
chr2
264140
278283
+
ALDOA
chr16
30064164
30070457
+
AC104109.3
chr5
134167170
134226071
-
ACADM
chr1
75724347
75787575
+
ACTB
chr7
5527148
5563784
-
ACAD9
chr3
128879596
128916067
+
ADM
chr11
10305073
10307397
+
AHSA1
chr14
77457870
77469472
+
AHCY
chr20
34280268
34311802
-
ACBD5
chr10
27195214
27242130
-
ACADVL
chr17
7217125
7225266
+
ABI1
chr10
26746593
26861087
-
ACAT2
chr6
159762045
159779112
+
ADCY3
chr2
24819169
24919839
-
AC003005.1
chr19
57487718
57517559
+
AJUBA
chr14
22971177
22982551
-
ACOT1
chr14
73537143
73543796
+
ALDH5A1
chr6
24494867
24537207
+
ACTR3
chr2
113890063
113962596
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-142-3p
chr17
58331245
58331267
-
hsa-miR-1244
chr2
231713368
231713393
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC007114.1
chr17
57071814
57085024
-
AC007952.4
chr17
19112000
19112636
-
AC010247.1
chr19
42132555
42137099
+
AC010327.5
chr19
55216660
55221616
+
AC026464.2
chr16
69463844
69466264
+
AC074032.1
chr12
50112197
50165618
+
AC091965.4
chr5
8444949
8445535
-
AC093157.1
chr1
101025844
101090513
+
AC139149.1
chr17
81514047
81527776
+
AC144548.1
chr12
110387463
110445548
-
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.