Entry Detail


General Information

Database ID:exR0511877
RNA Name:BAZ2A
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):56595596End Site(bp):56636816
External Links:ENSG00000076108



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMDC
chr11
77821109
77918432
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACVR1B
chr12
51951699
51997078
+
ADGRL2
chr1
81306160
81992436
+
AGPAT5
chr8
6708642
6761503
+
AK3
chr9
4709556
4742043
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-214-3p
chr1
172138816
172138837
-
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-491-5p
chr9
20716120
20716141
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-296-3p
chr20
58817626
58817647
-
hsa-miR-629-5p
chr15
70079427
70079447
-
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC067930.1
chr8
143579636
143580670
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.