Entry Detail


General Information

Database ID:exR0512037
RNA Name:BRD2
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):32968594End Site(bp):32981505
External Links:ENSG00000204256



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD15
chr17
29560547
29567037
-
ABHD2
chr15
89087459
89202355
+
ABL1
chr9
130713016
130887675
+
AC006030.1
chr2
74211604
74363377
-
AC073612.1
chr12
71674204
71698968
+
AC092143.1
chr16
89919165
89936092
+
AC098850.3
chr17
16690261
16804453
+
AC104532.1
chr19
5904841
5914707
+
AKIRIN2
chr6
87674860
87702233
-
AL162417.1
chr9
133098121
133163914
-
AL358113.1
chr9
69035747
69255187
+
ALDH5A1
chr6
24494867
24537207
+
ALDH6A1
chr14
74056847
74084492
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC021078.1
chr5
149494314
149504670
-
AC105339.2
chr15
82752884
82757208
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.