Entry Detail


General Information

Database ID:exR0512055
RNA Name:BRWD1
RNA Type:mRNA
Chromosome:chr21
Starnd:-
Coordinate:
Start Site(bp):39184176End Site(bp):39321559
External Links:ENSG00000185658



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB10
chr1
229516582
229558707
-
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC026954.2
chr17
7312661
7319174
-
AC068946.2
chr2
219209772
219222738
-
AC104452.1
chr3
49416777
49429314
-
ADCY9
chr16
3953387
4116442
-
ADGRG6
chr6
142301854
142446266
+
ADORA2A
chr22
24417879
24442357
+
ADPRHL2
chr1
36088892
36093932
+
AGAP3
chr7
151085831
151144436
+
AGO2
chr8
140520156
140635633
-
AL136295.1
chr14
24189157
24213473
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19a-3p
chr13
91350939
91350961
+
hsa-miR-23b-3p
chr9
95085265
95085287
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012146.1
chr17
5111468
5115004
+
AC016876.2
chr17
7581964
7584086
-
AC018521.1
chr17
47945424
47981736
+
AC067930.1
chr8
143579636
143580670
+
AD000090.1
chr19
35557956
35581954
+
AL096870.2
chr14
24209646
24215987
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.