Entry Detail


General Information

Database ID:exR0512394
RNA Name:CA12
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):63321378End Site(bp):63381846
External Links:ENSG00000074410



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADPRHL2
chr1
36088892
36093932
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-101-3p
chr1
65058442
65058462
-
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-204-5p
chr9
70810031
70810052
-
hsa-miR-211-5p
chr15
31065095
31065116
-
hsa-miR-195-5p
chr17
7017667
7017687
-
hsa-miR-324-5p
chr17
7223343
7223364
-
hsa-miR-431-5p
chr14
100881026
100881046
+
hsa-miR-432-5p
chr14
100884496
100884518
+
hsa-miR-520a-5p
chr19
53690895
53690915
+
hsa-miR-525-5p
chr19
53697547
53697567
+
hsa-miR-362-3p
chrX
50009005
50009026
+
hsa-miR-628-5p
chr15
55372991
55373012
-
hsa-miR-1278
chr1
193136552
193136573
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.