Entry Detail


General Information

Database ID:exR0512459
RNA Name:CALM1
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):90396502End Site(bp):90408268
External Links:ENSG00000198668



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF2
chr7
151207837
151227166
-
AC008758.1
chr19
12461559
12551474
-
AC010422.3
chr19
12643831
12648397
-
ACACB
chr12
109116595
109268226
+
ACTB
chr7
5527148
5563784
-
ACTL6A
chr3
179562886
179588407
+
ACTR2
chr2
65227753
65271253
+
ADCY6
chr12
48766194
48789037
-
ADNP
chr20
50888916
50931437
-
AFG3L2
chr18
12328944
12377227
-
AGO1
chr1
35869808
35930532
+
AGPAT1
chr6
32168212
32178096
-
AHCY
chr20
34280268
34311802
-
AKAP12
chr6
151239967
151358559
+
AL117348.2
chr1
225886696
225924278
-
AL136531.2
chr20
1317571
1393096
-
AL365205.1
chr6
41780349
41790141
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-206
chr6
52144401
52144422
+
hsa-miR-432-5p
chr14
100884496
100884518
+
hsa-miR-660-5p
chrX
50013256
50013277
+
hsa-miR-362-3p
chrX
50009005
50009026
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004812.2
chr12
120116907
120119000
+
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.