Entry Detail



General Information

Database ID:exR0512461
RNA Name:CALM3
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):46601074End Site(bp):46610782
External Links:ENSG00000160014



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ALDH6A1
chr14
74056847
74084492
-
ADAMTSL4
chr1
150549369
150560937
+
ABHD12
chr20
25294742
25390835
-
AGPAT1
chr6
32168212
32178096
-
ACOT13
chr6
24667035
24705065
+
AHCY
chr20
34280268
34311802
-
AGO1
chr1
35869808
35930532
+
ALDH7A1
chr5
126531200
126595362
-
AAMDC
chr11
77821109
77918432
+
ADAR
chr1
154582057
154628013
-
AHSA1
chr14
77457870
77469472
+
AC006486.1
chr19
42234583
42255132
-
AC010422.3
chr19
12643831
12648397
-
ABI2
chr2
203328239
203447728
+
AL121594.1
chr14
35122549
35317474
+
ALDH18A1
chr10
95605941
95656711
-
AC099811.2
chr17
42119674
42154916
-
ABCC5
chr3
183919934
184017939
-
ACTG1
chr17
81509971
81523847
-
AIF1L
chr9
131096476
131123152
+
AC245033.1
chr15
82536788
82573194
-
ACACA
chr17
37084992
37406836
-
ADAM19
chr5
157395534
157575775
-
ABTB1
chr3
127672935
127680926
+
ACTB
chr7
5527148
5563784
-
ACIN1
chr14
23058564
23095614
-
AGAP1
chr2
235494043
236131800
+
AC009133.6
chr16
29812261
29820092
+
AARSD1
chr17
42950526
42964498
-
AC090360.1
chr18
80034346
80097088
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-205-5p
chr1
209432166
209432187
+
hsa-miR-449a
chr5
55170586
55170607
-
hsa-miR-449b-5p
chr5
55170706
55170727
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC079781.5
chr7
97851688
97972985
-
AC093503.2
chr19
46609277
46610779
-
AC125807.2
chr12
3041437
3044950
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.