Entry Detail


General Information

Database ID:exR0512467
RNA Name:CALR
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):12938578End Site(bp):12944489
External Links:ENSG00000179218



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARSD1
chr17
42950526
42964498
-
ABCF2
chr7
151207837
151227166
-
ABHD14B
chr3
51968510
51983409
-
ABI1
chr10
26746593
26861087
-
ABRACL
chr6
139028745
139043302
+
AC005943.1
chr19
1578339
1605445
-
AC007192.1
chr19
18153158
18178117
+
AC069503.2
chr12
121888809
121921470
+
AC138811.2
chr16
18788063
18801519
-
ACAD8
chr11
134253495
134265855
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ACTR3
chr2
113890063
113962596
+
ADCYAP1R1
chr7
31052461
31111479
+
ADNP2
chr18
80109262
80147523
+
AHCY
chr20
34280268
34311802
-
AK3
chr9
4709556
4742043
-
AKAP8
chr19
15353385
15379798
-
AKT2
chr19
40230317
40285536
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-6515-5p
chr19
12940486
12940506
+
hsa-miR-6515-3p
chr19
12940521
12940540
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012236.1
chr15
31221999
31230838
-
AC026362.1
chr12
122975320
122982907
+
AC064802.1
chr8
114282067
114295839
+
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL021707.1
chr22
38739003
38749041
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.