Entry Detail


General Information

Database ID:exR0512490
RNA Name:CANX
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):179678628End Site(bp):179731641
External Links:ENSG00000127022



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
AAR2
chr20
36236459
36270918
+
AC005837.2
chr17
76732978
76738522
+
AC009133.6
chr16
29812261
29820092
+
AC010463.1
chr19
17267418
17282966
+
AC011511.4
chr19
10315471
10320678
-
AC078927.1
chr12
66123917
66169985
-
AC093323.1
chr4
6663396
6676755
+
AC131160.1
chr3
183815568
183884889
-
ACADVL
chr17
7217125
7225266
+
ACKR3
chr2
236567787
236582354
+
ACOT8
chr20
45841721
45857405
-
ACTG1
chr17
81509971
81523847
-
ACVR2B
chr3
38453890
38493142
+
ADAM9
chr8
38996869
39105261
+
ADAMTS1
chr21
26835755
26845409
-
ADGRA3
chr4
22345071
22516066
-
ADGRV1
chr5
90529344
91164437
+
ADH5
chr4
99070978
99088801
-
ADNP
chr20
50888916
50931437
-
AGO1
chr1
35869808
35930532
+
AGPAT1
chr6
32168212
32178096
-
AGPS
chr2
177392757
177559299
+
AIMP1
chr4
106315544
106349456
+
AKAP10
chr17
19904302
19978343
-
AKAP11
chr13
42272152
42323261
+
AKAP8L
chr19
15380050
15419141
-
AL589666.1
chr6
85557978
85615234
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-27a-3p
chr19
13836447
13836467
-
hsa-miR-27b-3p
chr9
95085505
95085525
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005618.1
chr5
141326210
141329357
+
AC012321.1
chr16
69703065
69704652
+
AC023509.1
chr12
53441741
53467528
+
AC107068.1
chr4
47840122
47844339
-
AC127459.1
chr16
23061406
23064173
-
AL118506.1
chr20
63861212
63864293
-
AL139089.1
chr13
52651305
52652279
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.