Entry Detail


General Information

Database ID:exR0512506
RNA Name:CAPNS1
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):36139953End Site(bp):36150353
External Links:ENSG00000126247



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCG2
chr4
88090150
88231628
-
AC007192.1
chr19
18153158
18178117
+
AC009690.1
chr15
72284727
72375981
-
AC010422.3
chr19
12643831
12648397
-
AC093525.1
chr16
2513965
2527955
+
AC099811.2
chr17
42119674
42154916
-
ACAP1
chr17
7336529
7351477
+
ACBD6
chr1
180269653
180502954
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACYP2
chr2
53970838
54305300
+
ADAM9
chr8
38996869
39105261
+
AKAP8L
chr19
15380050
15419141
-
AKR1A1
chr1
45550543
45570049
+
AL117348.2
chr1
225886696
225924278
-
AL136454.1
chr1
192716132
192716653
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-99a-5p
chr21
16539101
16539122
+
hsa-miR-100-5p
chr11
122152275
122152296
-
hsa-miR-147a
chr9
120244985
120245004
-
hsa-miR-206
chr6
52144401
52144422
+
hsa-miR-99b-5p
chr19
51692618
51692639
+
hsa-miR-769-5p
chr19
46018961
46018982
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.