Entry Detail


General Information

Database ID:exR0512574
RNA Name:CBS
RNA Type:mRNA
Chromosome:chr21
Starnd:-
Coordinate:
Start Site(bp):43053191End Site(bp):43076943
External Links:ENSG00000160200



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD16A
chr6
31686955
31703356
-
ABHD4
chr14
22598237
22613215
+
ABHD5
chr3
43690108
43734371
+
AC010323.1
chr19
8308283
8321379
-
AC010422.5
chr19
12664828
12669397
-
AC135050.2
chr16
31083439
31094956
-
AC138811.2
chr16
18788063
18801519
-
AC139530.2
chr17
81703371
81720539
+
AC245033.1
chr15
82536788
82573194
-
ACKR3
chr2
236567787
236582354
+
ACTA1
chr1
229431245
229434098
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ACTR3
chr2
113890063
113962596
+
ADRM1
chr20
62302093
62308862
+
AGBL5
chr2
27042364
27070622
+
AKAP1
chr17
57085092
57121346
+
AKR1A1
chr1
45550543
45570049
+
AL132780.3
chr14
22946270
22982258
-
AL162417.1
chr9
133098121
133163914
-
ALDH9A1
chr1
165662216
165698863
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6853-3p
chr9
35732974
35732995
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004951.4
chr7
43951910
44019151
-
AC026461.1
chr16
56682470
56687807
+
AC069281.2
chr7
100572232
100578700
-
AC074044.1
chr3
112990447
112991153
-
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL049796.1
chr1
93847174
93848939
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.