Entry Detail


General Information

Database ID:exR0512582
RNA Name:CBX3
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):26201162End Site(bp):26213607
External Links:ENSG00000122565



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD17C
chr15
80679684
80755621
+
AC004922.1
chr7
99325879
99394653
+
AC012254.2
chr18
47108188
47176345
-
AC068547.1
chr2
151802651
151973949
-
ACAD10
chr12
111686056
111757107
+
ACTB
chr7
5527148
5563784
-
AD000671.2
chr19
35739252
35745432
-
ADAR
chr1
154582057
154628013
-
ADCY1
chr7
45574140
45723116
+
ADGRG2
chrX
18989307
19122637
-
ADGRL2
chr1
81306160
81992436
+
ADM
chr11
10305073
10307397
+
ADSL
chr22
40346500
40390463
+
AK4
chr1
65147549
65232145
+
AKAP1
chr17
57085092
57121346
+
AKAP9
chr7
91940867
92110673
+
AKIP1
chr11
8911139
8920084
+
AL021546.1
chr12
120438198
120460006
+
AL022238.4
chr22
40346529
40410054
+
AL139300.1
chr14
103562962
103685924
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-629-5p
chr15
70079427
70079447
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011476.3
chr19
55006193
55048086
+
AC016876.2
chr17
7581964
7584086
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.