Entry Detail


General Information

Database ID:exR0512659
RNA Name:CCDC6
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):59788747End Site(bp):59906556
External Links:ENSG00000108091



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AC068580.4
chr11
1734821
1763954
-
AC093525.1
chr16
2513965
2527955
+
AC104109.3
chr5
134167170
134226071
-
ACBD4
chr17
45132600
45144181
+
ACTB
chr7
5527148
5563784
-
AFF4
chr5
132875395
132963634
-
AHCY
chr20
34280268
34311802
-
AL133352.1
chr10
100505628
100529881
-
AL928654.3
chr14
105487199
105492267
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
hsa-miR-20a-5p
chr13
91351072
91351094
+
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-106a-5p
chrX
134170244
134170266
-
hsa-miR-373-3p
chr19
53788748
53788770
+
hsa-miR-20b-5p
chrX
134169850
134169872
-
hsa-miR-520a-3p
chr19
53690933
53690954
+
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-873-5p
chr9
28888925
28888945
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC016876.2
chr17
7581964
7584086
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.