Entry Detail


General Information

Database ID:exR0512767
RNA Name:CCT2
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):69585426End Site(bp):69601570
External Links:ENSG00000166226



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
ABI2
chr2
203328239
203447728
+
AC104452.1
chr3
49416777
49429314
-
AC120057.2
chr17
7240427
7244635
-
AC124312.1
chr15
24955034
25000276
+
AC138811.2
chr16
18788063
18801519
-
ACER3
chr11
76860867
77026797
+
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ADNP
chr20
50888916
50931437
-
AGGF1
chr5
77029251
77065234
+
AKIRIN1
chr1
38991276
39006059
+
AL049629.2
chr11
33698261
33722467
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1244
chr2
231713368
231713393
+
hsa-miR-3609
chr7
98881700
98881723
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC005899.4
chr17
32328441
32329395
+
AD000090.1
chr19
35557956
35581954
+
AL049543.1
chr6
28587378
28591747
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.