Entry Detail


General Information

Database ID:exR0512768
RNA Name:CCT3
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):156308968End Site(bp):156367873
External Links:ENSG00000163468



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD4
chr14
22598237
22613215
+
AC004922.1
chr7
99325879
99394653
+
AC007192.1
chr19
18153158
18178117
+
AC009133.6
chr16
29812261
29820092
+
AC010323.1
chr19
8308283
8321379
-
AC010422.3
chr19
12643831
12648397
-
AC245033.1
chr15
82536788
82573194
-
ACOT13
chr6
24667035
24705065
+
ACP5
chr19
11574660
11579008
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN1
chr14
68874143
68979440
-
ADCY3
chr2
24819169
24919839
-
ADNP
chr20
50888916
50931437
-
AGAP4
chr10
45825594
45853875
-
AHCY
chr20
34280268
34311802
-
AL136454.1
chr1
192716132
192716653
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020663.1
chr16
4730115
4752565
-
AC079414.3
chr16
78123243
78124332
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.