Entry Detail


General Information

Database ID:exR0512771
RNA Name:CCT6A
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):56051685End Site(bp):56063989
External Links:ENSG00000146731



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABR
chr17
1003518
1229738
-
AC009133.6
chr16
29812261
29820092
+
AC015813.2
chr17
57989038
58007246
-
AC048338.1
chr12
122207779
122266423
-
AC058822.1
chr4
53377839
54295272
+
AC068547.1
chr2
151802651
151973949
-
AC090004.1
chr3
14135217
14148252
+
ACTL6A
chr3
179562886
179588407
+
ACTR2
chr2
65227753
65271253
+
ADD2
chr2
70607618
70768225
-
ADGRG6
chr6
142301854
142446266
+
AL365205.1
chr6
41780349
41790141
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-374b-5p
chrX
74218587
74218608
-
hsa-miR-3652
chr12
103930425
103930442
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC016065.1
chr8
6403551
6407142
-
AC016876.2
chr17
7581964
7584086
-
AC132217.1
chr11
2129121
2129964
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.