Entry Detail


General Information

Database ID:exR0512773
RNA Name:CCT7
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):73233420End Site(bp):73253021
External Links:ENSG00000135624



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
A1BG
chr19
58345178
58353492
-
ABHD16A
chr6
31686955
31703356
-
AC004832.3
chr22
30409255
30428990
+
AC010422.3
chr19
12643831
12648397
-
AC010463.1
chr19
17267418
17282966
+
AC011511.4
chr19
10315471
10320678
-
AC091167.2
chr15
90249556
90272208
+
AC092143.1
chr16
89919165
89936092
+
ACIN1
chr14
23058564
23095614
-
ACO1
chr9
32384603
32454769
+
ACOT7
chr1
6264269
6394391
-
ACTA2
chr10
88935074
88991339
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADA2
chr22
17178790
17258235
-
ADAMTS7
chr15
78759206
78811464
-
ADGRL1
chr19
14147743
14206187
-
ADI1
chr2
3497366
3519531
-
ADNP
chr20
50888916
50931437
-
AFMID
chr17
78187317
78207701
+
AGTRAP
chr1
11736084
11754802
+
AHCY
chr20
34280268
34311802
-
AIF1
chr6
31615217
31617021
+
AIF1L
chr9
131096476
131123152
+
AL136454.1
chr1
192716132
192716653
+
ALDH7A1
chr5
126531200
126595362
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012313.3
chr19
58346854
58362751
-
AC093904.4
chr2
9106593
9109865
+
AC133644.3
chr2
87455476
87767359
+
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.