Entry Detail


General Information

Database ID:exR0512835
RNA Name:CD52
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):26317958End Site(bp):26320523
External Links:ENSG00000169442



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC1
chr16
15949577
16143074
+
AC009690.1
chr15
72284727
72375981
-
AC099811.2
chr17
42119674
42154916
-
ACAD11
chr3
132558138
132660082
-
ACADS
chr12
120725774
120740008
+
ACLY
chr17
41866917
41930542
-
ACO2
chr22
41469117
41528989
+
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ACTR6
chr12
100199122
100241865
+
AGPAT3
chr21
43865223
43987592
+
AK4
chr1
65147549
65232145
+
AKR1A1
chr1
45550543
45570049
+
AL136454.1
chr1
192716132
192716653
+
AL669918.1
chr6
32813767
32838822
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-155-5p
chr21
25573983
25574006
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010327.5
chr19
55216660
55221616
+
AC026362.1
chr12
122975320
122982907
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.