Entry Detail


General Information

Database ID:exR0512848
RNA Name:CD74
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):150400041End Site(bp):150412929
External Links:ENSG00000019582



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AKT1
chr14
104769349
104795751
-
A4GALT
chr22
42692121
42721298
-
ACTN4
chr19
38647649
38731589
+
AHCY
chr20
34280268
34311802
-
ACTG1
chr17
81509971
81523847
-
AATF
chr17
36948954
37056871
+
AC006064.6
chr12
6556886
6607367
-
AC005258.1
chr19
2269525
2341172
+
AHCYL1
chr1
109984765
110023742
+
AC023055.1
chr12
55757275
55827546
-
AKAP8
chr19
15353385
15379798
-
ALDOA
chr16
30064164
30070457
+
ACTR3
chr2
113890063
113962596
+
ACTR2
chr2
65227753
65271253
+
AL049629.2
chr11
33698261
33722467
-
ACOT9
chrX
23701055
23766475
-
AK3
chr9
4709556
4742043
-
ACAP1
chr17
7336529
7351477
+
AC008982.1
chr19
38817471
38840178
-
ADGRE1
chr19
6887566
6940459
+
AL669918.1
chr6
32813767
32838822
-
AC007192.1
chr19
18153158
18178117
+
ACTB
chr7
5527148
5563784
-
AL590764.2
chrX
71103987
71111575
-
AKR1B1
chr7
134442356
134459284
-
ALDH18A1
chr10
95605941
95656711
-
AC005670.2
chr17
46923133
47049932
+
AIP
chr11
67483026
67491103
+
AKR7A2
chr1
19303965
19312146
-
ACIN1
chr14
23058564
23095614
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-24-3p
chr9
95086064
95086085
+
hsa-miR-7-5p
chr19
4770700
4770723
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-4687-3p
chr11
3856113
3856133
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC007952.4
chr17
19112000
19112636
-
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AL137802.2
chr1
16514645
16515754
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.