Entry Detail


General Information

Database ID:exR0513061
RNA Name:CFL1
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):65823022End Site(bp):65862026
External Links:ENSG00000172757



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AKAP8
chr19
15353385
15379798
-
AC004922.1
chr7
99325879
99394653
+
AL133352.1
chr10
100505628
100529881
-
AHCYL2
chr7
129225023
129430211
+
AC010422.6
chr19
12525720
12580975
-
AHCY
chr20
34280268
34311802
-
AFDN
chr6
167826922
167972023
+
ALDH6A1
chr14
74056847
74084492
-
AC073082.1
chr2
48632291
48755724
-
AEN
chr15
88621337
88632281
+
ACTG1
chr17
81509971
81523847
-
AFG3L2
chr18
12328944
12377227
-
AASDHPPT
chr11
106075501
106098699
+
AHNAK2
chr14
104937244
104978374
-
AKT2
chr19
40230317
40285536
-
ACTB
chr7
5527148
5563784
-
ADPRH
chr3
119579268
119589945
+
AC092647.5
chr7
55887277
55955239
+
ACBD3
chr1
226144679
226186741
-
ABCB7
chrX
75051048
75156732
-
ACTA1
chr1
229431245
229434098
-
ABI1
chr10
26746593
26861087
-
AC011462.1
chr19
41350853
41425001
+
AKR1C1
chr10
4963253
4983283
+
ACAT2
chr6
159762045
159779112
+
AC010463.1
chr19
17267418
17282966
+
AC010422.3
chr19
12643831
12648397
-
AKAP12
chr6
151239967
151358559
+
AKR1B1
chr7
134442356
134459284
-
AC009133.6
chr16
29812261
29820092
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-155-5p
chr21
25573983
25574006
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC004687.1
chr17
58330884
58332508
-
AC007952.4
chr17
19112000
19112636
-
AC026362.1
chr12
122975320
122982907
+
AC132217.1
chr11
2129121
2129964
-
AC144548.1
chr12
110387463
110445548
-
ADARB2-AS1
chr10
1526637
1556984
+
AFDN-DT
chr6
167822103
167826812
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.