Entry Detail


General Information

Database ID:exR0513094
RNA Name:CHD2
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):92900189End Site(bp):93027996
External Links:ENSG00000173575



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC013394.1
chr15
92883413
92949230
+
AC137834.1
chr12
57249609
57296484
-
ACTB
chr7
5527148
5563784
-
ADAMTS1
chr21
26835755
26845409
-
AGRN
chr1
1020120
1056118
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-106a-5p
chrX
134170244
134170266
-
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-20b-5p
chrX
134169850
134169872
-
hsa-miR-520c-3p
chr19
53707506
53707527
+
hsa-miR-520d-3p
chr19
53720149
53720170
+
hsa-miR-488-3p
chr1
177029374
177029394
-
hsa-miR-532-3p
chrX
50003204
50003225
+
hsa-miR-1286
chr22
20249145
20249165
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067852.1
chr17
42536510
42562062
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.