Entry Detail


General Information

Database ID:exR0513208
RNA Name:CKAP5
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):46743048End Site(bp):46846308
External Links:ENSG00000175216



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB8
chr7
151028422
151047782
+
AC068580.4
chr11
1734821
1763954
-
ACAA2
chr18
49782164
49813953
-
ACADM
chr1
75724347
75787575
+
ACBD5
chr10
27195214
27242130
-
ACTR2
chr2
65227753
65271253
+
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-20a-5p
chr13
91351072
91351094
+
hsa-miR-320a-3p
chr8
22244975
22244996
-
hsa-miR-320b
chr1
224257049
224257070
-
hsa-miR-320c
chr18
24321716
24321735
+
hsa-miR-4485-3p
chr11
10508277
10508296
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL049543.1
chr6
28587378
28591747
+
AL109976.1
chr20
3239705
3245382
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.