Entry Detail


General Information

Database ID:exR0513209
RNA Name:CKB
RNA Type:mRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):103519667End Site(bp):103522833
External Links:ENSG00000166165



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AHNAK
chr11
62433542
62556235
-
AL513165.2
chr9
37512547
37592469
-
AC093525.2
chr16
2496032
2520218
+
AC068580.4
chr11
1734821
1763954
-
AL669918.1
chr6
32813767
32838822
-
AC116366.3
chr5
132410832
132646079
+
ACADVL
chr17
7217125
7225266
+
AHCY
chr20
34280268
34311802
-
AL136295.1
chr14
24189157
24213473
-
AHSA1
chr14
77457870
77469472
+
AATF
chr17
36948954
37056871
+
AC069503.2
chr12
121888809
121921470
+
ADD1
chr4
2843857
2930076
+
ALDH9A1
chr1
165662216
165698863
-
AKAP8L
chr19
15380050
15419141
-
AFF1
chr4
86935002
87141054
+
AL121845.3
chr20
63708864
63739103
+
ACACA
chr17
37084992
37406836
-
AGO2
chr8
140520156
140635633
-
ALDOA
chr16
30064164
30070457
+
ACOT7
chr1
6264269
6394391
-
AC010132.3
chr7
42909273
42932174
-
AC011448.1
chr19
19516227
19536076
+
AIF1L
chr9
131096476
131123152
+
AKR1B1
chr7
134442356
134459284
-
AGAP1
chr2
235494043
236131800
+
AL360181.3
chr10
133380017
133420271
+
ACTB
chr7
5527148
5563784
-
AC010323.1
chr19
8308283
8321379
-
ACTG1
chr17
81509971
81523847
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010729.1
chr2
5726253
5730355
+
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC026471.1
chr16
31456711
31459736
-
AC093827.4
chr4
86924630
86936202
-
AC108134.2
chr16
3156736
3157483
-
AL049795.2
chr1
32170733
32176568
+
AL133367.1
chr14
103525010
103529072
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.